L-Theanine: What is L Theanine?
L-Theanine: What is L-Theanine?
L-Theanine is an amino acid derived from tea leaves actively penetrates into the brain through the blood-brain barrier, exhibit psychoactive properties: it reduces the effects of stress, increases cognition and elevates mood, acting synergistically with caffeine. It was established experimentally that taking about 200 mg L-Theanine the brain subjects 30 minutes after changing its activity, to form predominantly alpha-waves.
How does L-Theanine work
In order to ensure that the needs of the body and the mind, the brain uses the braking system, which can permeate all parts of the brain to its working substance, the brake mediator of the brain. This is GABA. If the activity of this system in a particular area of the brain is broken, there is a hotbed of uncontrollable excitement. This distorts the functioning of the organism in that department, which is responsible for this area of the brain, and may take possession of and other parts of the brain that directly leads to epileptic seizures. At the same time, each subsequent seizure will be more to destroy the brake system, respectively epilepsy will progress. Accordingly, a need in the consumption of drugs that could control the braking system is paramount. Unfortunately, the use of GABA as an injection, tablet, or any other drugs ineffective because the acid will not enter the brain because of the presence of blood-brain barrier (i.e., a barrier exists between the blood and brain). Thus, drugs that have a similar effect, although to penetrate through the barrier, but are not effective as feedback, or generally have side effects.
L-Theanine is structurally similar to glutamate CNS neurotransmitter chemical, and providing very little effects on AMPA and NMDA receptors, nevertheless, capable of raising the level of dopamine, which has the effect of improving mood and increased endurance performance during training. Furthermore, there is evidence that L-Theanine may raise the level of GABA.
Short term and long term effects
Our body produces natural brake fluid, which helps to control the mind – GABA, but hormonal disorders in the body of its production may be reduced, and as a result a person begins to experience depression, anger, apathy. In patients with epilepsy, natural brake centers are gradually destroyed, making each seizure stronger and develop their body every day is becoming weaker. A drug L-Theanine, due to components within its structure, just helps our body to replenish GABA. L-Theanine supports the work of the heart and the brain, reduces anxiety and improves mood.
When brewing tea, the person gets at most a small number of Theanine (Theanine) as it is strongly associated with the molecular structures of the leaf, and the usual brewing is not able to completely release it into the solution. Only a stringent condition boiling at an elevated pressure, when the water rises to t 127 ° C, allows one to fully extract Theanine (L-Theanine) in solution.
L-Theanine Dosage and suggested usage
Tea contains 2 isomers of theanine, of which 98% are L-theanine and the remaining 1-2% present is theanine. One cup (200 ml) Green tea contains 9-14 mg of theanine, and black tea – further 14-18 mg. 50 mg of theanine enough to feel its effect on brain activity. Theanine penetrates into the brain and begins to affect its activity after about 30 minutes after exposure. Impact of theanine on the brain takes about 5 hours. Therapeutic daily dose of L-Theanine is 200 mg.
L-Theanine does not cause addiction, overdose and side effects. It is a natural relaxant; it is completely safe to use in the daytime. L-Theanine is not recommended for pregnant women and nursing mothers, and in the morning and daytime – drivers and people whose skills require maximum concentration and attention span (it can take Theanine before bedtime). Before taking this medication should consult a doctor. L-Theanine be taken one hour before or 2 hours after breakfast and dinner 1 capsule (2 times daily).
Additional Information on L-Theanine
L-Theanine is a non-essential amino acid and glutamic acid analog commonly found in various types of tea. L-Theanine crosses the blood-brain barrier readily giving it its psychoactive properties. L-Theanine is an analog of glutamate, which is an essential neurotransmitter implicated in improving learning and memory processes. It was first extracted from a gyokuro leaf in 1950 by a lab in Kyoto after its discovery in 1949.
L-Theanine stimulates the GABA receptor and is a fat-soluble nootropic. Due to L-Theanine being an analog of glutamine, it has been shown to be an effective treatment for not only mental stress, but physical stress as well. Many studies have shown L-Theanine to be an anxiolytic, potentially due to increasing the dopamine levels.
L-Theanine does not just improve scores on tests of learning and memory; it also affects many other variables. L-Theanine has been shown to lower blood pressure, and anxiety. It has also been shown to aid in the improvement of the body’s immune system by increasing the amount of afflictions fighting gamma delta T-Cells, and increasing antibacterial proteins.
One study showed that L-Theanine prevents memory impairment in cases related to repeated Cerebral Ischemia in rats. This study also showed that L-Theanine has neuro protective qualities in regard to combating against neuronal cell death, making it a plausible treatment for cerebrovascular diseases such as cerebral thrombosis and cerebral embolism. Egashira, N., Ishigami, N., Pu, F., Mishima, K., Iwasaki, K., Orito, K., Oishi, R. and Fujiwara, M. (2008), Theanine prevents memory impairment induced by repeated cerebral ischemia in rats. Phytother. Res., 22: 65–68. doi: 10.1002/ptr.2261.
A recent double-blind placebo-controlled study showed that L-Theanine enhances the memory and attentiveness in patients suffering from mild cognitive inability. The study showed that brain theta waves, which are implicated in cognitive attentiveness, were increased in the temporal, frontal, parietal, and occipital areas of the brain. The conclusion of the 16 week-long study showed L-Theanine as a plausible treatment for improving cognition and memory. Sang-Ki Park, In-Chul Jung, Won Kyung Lee, Young Sun Lee, Hyoung Kook Park, Hyo Jin Go, Kiseong Kim, Nam Kyoo Lim, Jin Tae Hong, Sun Yung Ly, and Seok Seon Rho. Journal of Medicinal Food. April 2011, 14(4): 334-343. doi:10.1089/jmf.2009.1374.
L-Theanine was shown to reduce the amount of psychological and physiological stress in a double-blind study on 12 participants. When administered L-Theanine the subjects’ heart rates were reduced as well as salivary immunoglobulin. The study was conducted through 4 different scenarios, and its conclusion was that L-Theanine could cause anti-stress effects through suppressing cortical neuron excitation. Biol Psychol. 2007 Jan; 74(1): 39-45 Epub 2006 Aug 22. L-Theanine reduces psychological and physiological stress responses.
The recommended L-Theanine dosage is usually 200-400 mg per day, taken in two 200 mg doses, one in the morning and one in the afternoon. L-Theanine is sold in both tablet and powder form, generally of 200 mg each.
Does L-Theanine Work?
L-Theanine is a non-essential amino acid that is promoted as a natural method of improving cognitive functions and relaxation. There have been clinical studies to suggest L-Theanine can improve memory, focus, and reduce stress levels. This is accomplished through increasing the activity of various neuro receptors and transmitters of the brain.
There are still many variables though that have to be looked at with improving cognitive abilities. As a result, it is very hard to determine just how effective L-Theanine would be for a specific person. It all comes down to their own needs and current cognitive ability as well as lifestyle choices.