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Adrafinil: Usage, Dosage and Effects

Adrafinil: What is this compound?

Adrafinil Usage, Dosages and Effects

Adrafinil and its Efficacy

Falling under the category of Eugeroic, a kind of Nootropic agent, Adrafinil helps in improving concentration and alertness. It is a class of stimulant, which helps fight sleepiness, exhaustion and fatigue for a longer duration. Because of this feature, it is very helpful to the workers who engage in the night shift or who work for prolonged hours. According to Milgram Callahan and Siwak (2006), Adrafinil is a smart drug that effects in activating behavior but is devoid of the ill-effects of other stimulants in this category.
Adrafinil Dosage
Adrafinil works mainly in two ways. First, this nootropic may boost the level of neurotransmitter hypo cretin, which increases wakefulness and concentration. Additionally, further increased dosage of the drug can cause more attention-stimulating chemicals in human body and reduces tiredness. Second, this concentration-improving drug facilitates learning process by stimulating brain attentiveness and memory. Accomplished by the breakdown of Glutamate in the body. Considering it stimulates the release of glutamate, thereby improving cognitive and perceptive abilities in human beings. In addition, it is also worth noting that no exact method has yet been defined for the functionality of this nootropic.

 

Dosage and Suggested Usage of Adrafinil

The ideal dosage of this compound is between 600-1200mg (Kurtis Frank, Bill Willis, Kamal Patel, Gregory Lopez, Dbarvinok, 2014). Water and juice can be used to take Adrafinil since it is water soluble. Above all, take Adrafinil in the morning since taking this in the afternoon or evening can cause insomnia. With this in mind, patients should use in lower quantities to start with, and can gradually increase to higher suggested dosages.

Take Adrafinil on an occasional basis. Such as, taking on days when stringent deadlines are to be met or when a job demands extra working hours to be put in. You can also take this drug on a cyclic basis. For example, one could take this drug for two weeks and then take a break for a week. As a result doing this can reduce adverse effects on the liver.

 

Short Term and Long Term Effects of Adrafinil

Considered safe in short period usage, and as an alertness promoting agent in short period usage. In particular, it stimulates the cognitive and perceptive abilities in human beings. Additionally, studies indicate that use of this drug can also affect the motivational state of people.

It is suggested not to use Adrafinil for long term periods. Instead, the drug can be taken in cycles. For example, if taken for the long-run, the body can develop tolerance against the drug and its effect will not be felt. Similarly, in long-term use, it can render people to change their behavioral attributes, like laconic people can become more talkative. This nootropic is being effectively used for the treatment of Alzheimer disease in France (Heather M. Callahan, 2001).

 

Side effects of Adrafinil

The common symptoms of the drug are headaches, stomach problems and elevated blood pressure. For example, high dosages can potentially cause a decrease in the frequency of urine (Siwak CT1 et.al, 2000). Furthermore, it may render people to daydream or hallucinate. In particular, the drug may also cause liver damages, epilepsy and kidney failure with the prolonged use.

Adrafinil has positive usages for human beings as it improves the cognitive abilities of people temporarily. As a result, it is beneficial for people doing extra-hours of work or people working odd-hour shifts. However, this drug has contra-indications as well. Therefore, its use needs to be monitored and moderated.

 

Additional Information about this nootropic

Originally discovered in the 1970’s in France by pharmaceutical company Group Lafon. Adrafinil is a central nervous system stimulant that helps relieve sleepiness and improve overall alertness. Metabolized in the liver, the eurgeric Adrafinil becomes Modafinil.


Adrafinil, while commonly considered a stimulant does not stimulate motor coordination like other stimulants, and is primarily a cerebral stimulant. Subsequently, connected with a stimulation of Hypocretin, this drug increases how alert and awake one feels. As a result, higher level of Hypocretin causes an increase in dopamine, norepinephrine, and histamines. All three of these plays a role in overall energy levels, making this substance a choice nootropic to take before an intense workout or long study session. It may also stimulate glutamatergic receptors. These receptors are used in thought and learning processes, and may help potentiate either Aniracetam or Piracetam. This compound was prescribed in France in 1986 as a treatment for narcolepsy due to the compounds effects of wakefulness and alertness.
Adrafinil Stimulant
Adrafinil is used not only to help with studying sessions, but is also given to French pilots in case of emergency. Consequently, this smart drug is currently on the forbidden list in competitive sports, because of its stimulant like behaviors. Pharmacological approach to desynchronization of the sleep-wakefulness cycle in the military and sport environment (Ann Pharm Fr. 2007 Jul;65(4):258-64).

In fact, Adrafinil was shown to improve the learning abilities of aged beagle dogs in one study. The study was against a placebo, and the beagles administered this compound demonstrated both lowered error counts. Oral administration of adrafinil improves discrimination learning in aged beagle dogs (Pharmacol Biochem Behav. 2000 Jun;66(2):301-5).

Related Articles:

Adrafinil vs Modafinil: Comparisons, Effects and Dosage

Adrafinil Recommended Dosage

The recommended dose of Adrafinil is 600mg taken up to twice a day taken in the morning or evening time. Sold in capsules, powder and tablet form.

Does Adrafinil Work?

Adrafinil is a stimulatory drug that is used by late shift workers, or early-morning workers to help improve alertness and increase the feeling of wakefulness. Shown to help increase overall motivation possibly due to its positive effects in regard to dopamine receptors.

However, there are still many variables though that have to be looked at with improving cognitive abilities. Therefore, it is very hard to determine just how effective this smart drug would be for a specific person. In conclusion, it all comes down to their own needs and current cognitive ability as well as lifestyle choices.

Where to buy Adrafinil Capsules?

Smart Drugs for Thought carries premium quality adrafinil capsules and are always in stock.  The adrafinil capsules contains 300mg each and are encapsulated with vegetarian capsules.  In addition, every bottle contains 30 x 300mg adrafinil capsules.

Adrafinil Dosage Benefits Effects

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