Adrafinil: What is Adrafinil?
Adrafinil and its Efficacy
Adrafinil comes under the category of Eugeroic, a kind of Nootropic agent, which helps in improving concentration and alertness. It is a class of stimulant, which helps fight sleepiness, exhaustion and fatigue for a longer duration. Because of this feature, it is very helpful to the workers who engage in the night shift or who work for prolonged hours. According to Milgram Callahan and Siwak (2006), Adrafinil is a smart drug that effects in activating behavior but is devoid of the ill-effects of other stimulants in this category.
Adrafinil works mainly in two ways. First, Adrafinil helps boost the level of neurotransmitter hypo cretin, which increases wakefulness and concentration. Further increased dosage of the drug can cause more attention-stimulating chemicals in human body and reduces tiredness. Second, this concentration-improving drug facilitates learning process by stimulating brain attentiveness and memory. This is done through the breakdown of Glutamate in the body. It stimulates the release of Glutamate, thereby improving cognitive and perceptive abilities in human beings. It is also worth noting that no exact method has yet been defined for the functionality of Adrafinil.
Dosage and Suggested Usage of Adrafinil
The ideal dosage of Adrafinil is between 600-1200mg (Kurtis Frank, Bill Willis, Kamal Patel, Gregory Lopez, Dbarvinok, 2014). Adrafinil is water soluble and can be taken with water or juice on an empty stomach. It should be taken in the morning since taking this in the afternoon or evening can cause insomnia. Patients should take Adrafinil in lower quantities to start with, and can gradually elevate to higher recommended dosages.
Adrafinil should be taken on an occasional basis. For instance, it could be taken on days when stringent deadlines are to be met or when a job demands extra working hours to be put in. The drug can also be taken on a cyclic basis. For example, one could take this drug for two weeks and then take a break for a week. This way, adverse effects of the drug on liver can be reduced.
Short Term and Long Term Effects of Adrafinil
Use of Adrafinil is considered to be safe in short period usage. In short period use, the drug is considered as an alertness promoting agent. It stimulates the cognitive and perceptive abilities in human beings. Studies indicate that use of this drug can also affect the motivational state of people.
The use of Adrafinil is not suggested for long term. Instead, the drug can be taken in cycles. If taken for the long-run, the body can develop tolerance against the drug, and its effect will not be felt. In long-term use, it can render people to change their behavioral attributes, like laconic people can become more talkative. Adrafinil is being effectively used for the treatment of Alzheimer disease in France (Heather M. Callahan, 2001).
Side effects of Adrafinil
The common symptoms of the drug are headaches, stomach problems and elevated blood pressure. High dosage of Adrafinil can potentially cause a decrease in the frequency of urine (Siwak CT1 et.al, 2000). It may render people to daydream or hallucinate. The drug may also cause liver damages, epilepsy and kidney failure with the prolonged use.
Adrafinil has positive usages for human beings as it improves the cognitive abilities of people temporarily. It is beneficial for people doing extra-hours of work or people working odd-hour shifts. However, it is to be noted that this drug has contra-indications as well. Therefore, its use needs to be monitored and moderated.
Adrafinil Additional Information
Adrafinil was originally discovered in the 1970’s in France by pharmaceutical company Group Lafon. Adrafinil is a central nervous system stimulant that helps relieve sleepiness and improve overall alertness. Adrafinil, being eurgeric, is metabolized in the liver into Modafinil, which is a prescription drug known as Provigil.
Adrafinil, while commonly considered a stimulant does not stimulate motor coordination like other stimulants, and is primarily a cerebral stimulant. Connected with a stimulation of Hypocretin, this drug increases how alert and awake one feels. A higher level of Hypocretin causes an increase in dopamine, norepinephrine, and histamines. All three of these plays a role in overall energy levels, making this substance a choice nootropic to take before an intense workout or long study session. It may also stimulate glutamatergic receptors, which are used in thought and learning processes and may help potentiate either Aniracetam or Piracetam. Adrafinil was prescribed in France in 1986 as a treatment for narcolepsy due to its effects of wakefulness and alertness.
Adrafinil, while commonly considered a stimulant does not stimulate motor coordination like other stimulants, and is primarily a cerebral stimulant. Connected with a stimulation of Hypocretin, this drug increases how alert and awake one feels. A higher level of Hypocretin causes an increase in dopamine, norepinephrine, and histamines. All three of these play a role in overall energy levels, making this substance a choice nootropic to take before a intense workout or long study session. It may also stimulate glutamatergic receptors, which are used in thought and learning processes and may help potentiate either Aniracetam or Piracetam. Adrafinil was prescribed in France in 1986 as a treatment for narcolepsy due to its effects of wakefulness and alertness.
Adrafinil is used not only to help with studying sessions, but is also given to French pilots in case of emergency. Adrafinil is currently on the forbidden list in competitive sports due to its stimulant like behaviors. Pharmacological approach to desynchronization of the sleep-wakefulness cycle in the military and sport environment (Ann Pharm Fr. 2007 Jul;65(4):258-64).
In one study, Adrafinill was shown to improve the learning abilities of aged beagle dogs. The study was against a placebo, and the beagles administered Adrafinil demonstrated both lowered error counts. Oral administration of adrafinil improves discrimination learning in aged beagle dogs (Pharmacol Biochem Behav. 2000 Jun;66(2):301-5).
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Adrafinil Recommended Dosage
The recommended dose of Adrafinil is 600mg taken up to twice a day taken in the morning or evening time. This cognitive enhancer is sold in capsules, powder, and tablet form.
Does Adrafinil Work?
Adrafinil is a stimulatory drug that is used by late shift workers, or early-morning workers to help improve alertness and increase the feeling of wakefulness. This drug has also been shown to help increase overall motivation possibly due to its positive effects in regard to dopamine receptors.
There are still many variables though that have to be looked at with improving cognitive abilities. As a result, it is very hard to determine just how effective this smart drug would be for a specific person. It all comes down to their own needs and current cognitive ability as well as lifestyle choices.
Where to buy Adrafinil Capsules?
Smart Drugs for Thought carries premium quality adrafinil capsules and are always in stock. The adrafinil capsules contains 300mg each and are encapsulated with vegetarian capsules. Every bottle contains 30 x 300mg adrafinil capsules.