Adrafinil: What is Adrafinil? By SmartDrugsforThought

Adrafinil was originally discovered in the 1970’s in France by pharmaceutical company Group Lafon. Adrafinil is a central nervous system stimulant that helps relieve sleepiness and improves overall alertness. Adrafinil, being eurgeric, is metabolized in the liver into Modafinil, which is a prescription drug known as Provigil.

Adrafinil, while commonly considered a stimulant does not stimulate motor coordination like other stimulants, and is primarily a cerebral stimulant. Connected with a stimulation of Hypocretin, Adrafinil increases how alert and awake one feels. A higher level of Hypocretin causes an increase in dopamine, norepinephrine, and histamines. All three of these play a role in overall energy levels, making Adrafinil a choice nootropic to take before a intense workout or long study session. It may also stimulate glutamatergic receptors, which are used in thought and learning processes and may help potentiate either Aniracetam or Piracetam. Adrafinil was prescribed in France in 1986 as a treatment for narcolepsy due to its effects of wakefulness and alertness.

Adrafinil is used not only to help with studying sessions, but is also given to French pilots in case of emergency. Adrafinil is currently on the forbidden list in competitive sports due to its stimulant like behaviors. Pharmacological approach to desychronization of the sleep-wakefulness cycle in the military and sport environment (Ann Pharm Fr. 2007 Jul;65(4):258-64).

In one study Adrafinil was shown to improve the learning abilities of aged beagle dogs. The study was against a placebo, and the beagles administered Adrafinil demonstrated both lowered error counts. Oral administration of adrafinil improves discrimination learning in aged beagle dogs (Pharmacol Biochem Behav. 2000 Jun;66(2):301-5).

Adrafinil Dosage

The recommended dose of Adrafinil is 300mg taken up to twice a day taken in the morning or evening time. Adrafinil is sold in capsules, powder, and tablet form.Adrafinil

Does Adrafinil Work?

Adrafinil is a stimulatory drug that is used by late shift workers, or early morning workers to help improve alertness and increase the feeling of wakefulness. Adrafinil has also been shown to help increase overall motivation possibly due to its positive effects in regards to dopamine receptors.

There are still many variables though that have to be looked at with improving cognitive abilities. As a result, it is very hard to determine just how effective Adrafinil would be for a specific person. It all comes down to their own needs and current cognitive ability as well as lifestyle choices.


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