Phenylpiracetam, What is it?
Phenylpiracetam is widely believed to have first been created in Russia in the early 1990′s, but Soviet journals from 1983 held information regarding it under the name of “Carphedron”. Pharmacological studies have shown that Phenylpiracetam stimulates certain neuronal receptors in the Central Nervous System (CNS) that are involved in memory and thought processes, such as the acetylcholine transmitters, GABA receptors, and NDMA receptors. Phenylpiracetam has also shown to increase dopamine receptors (D1, D2, and D3) activity.
Phenylpiracetam is a water-soluble nootropic of the racetam chemical class purported to be 30 to 60 times more potent than Piracetam, and the strongest Racetam to date. Phenylpiracetam not only improves cognitive functions and thought processes, but has also shown usefulness in physical conditioning through helping increase stamina as well as improve one’s tolerance to cold. Phenylpiracetam has been found to have a high oral bioavailability compared to other Racetams, with a 3 to 5 hour half life in humans.
Phenylpiracetam was shown in a clinical study to have a wider and more effective range of benefits in comparison with Piracetam. Phenylpiracetam was shown to improve memory functions, problem solving skills, and attention switching. Drugs. 2010 Feb 12;70(3):287-312. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.
Another study showed Phenylpiracetam had a wide range of benefits including increased locomotion skills, antidepressant benefits, and memory enhancement. This series of tests was recently done on rats after only one administration of the nootropic Phenylpiracetam. Basic Clin Pharmacol Toxicol. 2011 Nov;109(5):407-12. Investigation into stereoselective pharmacological activity of phenotropil.
In one study done on rats that had LPS-induced immune stress Phenylpiracetam when used showed an increase in horizontal locomotion, prevention of apprehension and fear response. Showing that Phenylpiracetam promotes psychoimmunomodularory effects. Bull Exp Biol Med. 2011 May;151(1):51-4. Psychoimmunomodulatory effect of phenotropil in animals with immune stress.
The recommended Phenylpiracetam dosage is usually 200 mg per day, taken in two 100 mg doses, one in the morning and one in the afternoon. It is sold in both tablet and powder form, generally of 100 mg each.
Does Phenylpiracetam Work?
Phenylpiracetam is a Nootropic that is promoted as a natural method of improving cognitive functions, energy, focus, and locomotive abilities. There has been several clinical studies that have shown Phenylpiracetam to have a stronger effect than Piracetam, and a wider range of benefits. Some of the reported benefits include preventing some fear anxiety and depression, increased locomotor functionality, as well as improved immunoreactivity.
There are still many variables that are necessary to be looked at with improving cognitive abilities. As a result, it is very hard to determine just how effective Phenylpiracetam would be for a specific person. It all comes down to their own needs and current cognitive ability as well as lifestyle choices.